ZFIN is now using GRCz12tu for Genomic Data
Gene
cpt1a2b
- ID
- ZDB-GENE-050417-155
- Name
- carnitine palmitoyltransferase 1A2b
- Symbol
- cpt1a2b Nomenclature History
- Previous Names
-
- cpt1cb (1)
- si:dkey-16p21.4
- zgc:112484
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable carnitine O-palmitoyltransferase activity. Predicted to be involved in carnitine metabolic process and fatty acid metabolic process. Predicted to be active in mitochondrion. Is expressed in EVL; periderm; and polster. Human ortholog(s) of this gene implicated in carnitine palmitoyltransferase I deficiency; hereditary spastic paraplegia 73; and lipid metabolism disorder. Orthologous to several human genes including CPT1C (carnitine palmitoyltransferase 1C).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:112484 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| carnitine palmitoyltransferase I deficiency | Alliance | CPT deficiency, hepatic, type IA | 255120 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR032476 | Carnitine O-palmitoyltransferase, N-terminal |
| Domain | IPR039551 | Choline/Carnitine o-acyltransferase, domain 1 and 2 |
| Family | IPR000542 | Acyltransferase ChoActase/COT/CPT |
| Homologous_superfamily | IPR023213 | Chloramphenicol acetyltransferase-like domain superfamily |
| Homologous_superfamily | IPR042231 | Choline/Carnitine o-acyltransferase, domain 2 |
Domain Details Per Protein
| Protein | Additional Resources | Length | Acyltransferase ChoActase/COT/CPT | Carnitine O-palmitoyltransferase, N-terminal | Chloramphenicol acetyltransferase-like domain superfamily | Choline/Carnitine o-acyltransferase, domain 1 and 2 | Choline/Carnitine o-acyltransferase, domain 2 |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PFB6 | InterPro | 807 | |||||
| UniProtKB:A0A8M9PYA7 | InterPro | 393 | |||||
| UniProtKB:A0A8M9Q999 | InterPro | 409 | |||||
| UniProtKB:E7EYD4 | InterPro | 780 | |||||
| UniProtKB:A0A8M3B117 | InterPro | 394 | |||||
| UniProtKB:A0AC58J2G5 | InterPro | 807 | |||||
| UniProtKB:A0AC58J2G6 | InterPro | 708 | |||||
| UniProtKB:A0AC58J2G8 | InterPro | 780 | |||||
| UniProtKB:A0AC58J2I8 | InterPro | 409 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cpt1cb-202
(1)
|
Ensembl | 2,541 nt | ||
| mRNA |
cpt1cb-203
(1)
|
Ensembl | 1,608 nt | ||
| ncRNA |
cpt1cb-002
(1)
|
Ensembl | 858 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers